BiologyAdvanced18 min read

Prokaryotes, Protista & Viruses

Bacteria, single-celled eukaryotes, and the viruses on the edge of life

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Practise the full question bank:

01

Kingdom Prokaryotae — the bacteria

The bacteria are single prokaryotic cells: they have no nucleus and no membrane-bound organelles, their DNA lying free as a single circular loop, sometimes with small extra rings called plasmids. A tough cell wall gives them shape, and many have a flagellum to move. They reproduce very fast by simple binary fission.

Bacteria are everywhere and enormously important — decomposers that recycle nutrients, nitrogen-fixers that feed plants, and the microbes behind yoghurt and antibiotics — though some cause disease.

02

Kingdom Protista

The protists are a mixed kingdom of mostly single-celled eukaryotes — they do have a nucleus and organelles. Some are animal-like (the Amoeba and Paramecium, which hunt and engulf food), and some are plant-like (algae, which photosynthesise). A few cause serious disease, such as the Plasmodium that causes malaria.

GroupCell typeExample
Prokaryotaeprokaryotic (no nucleus)bacteria
Protista (animal-like)eukaryoticAmoeba
Protista (plant-like)eukaryoticalgae
03

Viruses — on the edge of life

Viruses are not placed in any kingdom, because they are not truly alive by the usual tests. A virus is just genetic material (DNA or RNA) inside a protein coat. It cannot respire, grow or reproduce on its own — it must invade a living host cell and hijack the cell's machinery to make copies of itself, usually destroying the host cell. Viruses cause diseases such as flu, measles and COVID-19, and antibiotics do not affect them.

Why viruses are not "alive"

A virus shows none of the characteristics of life on its own — no respiration, no growth, no independent reproduction. It only replicates by taking over a host cell, which is why it sits outside the five kingdoms.

04

A worked example

Worked example

Give two structural differences between a bacterial cell and a human (animal) cell, and explain why a virus is not classed as a living organism.

  1. A bacterial cell has no nucleus (its DNA is a free circular loop); a human cell has a nucleus.Bacteria are prokaryotic, human cells eukaryotic.
  2. A bacterial cell has no membrane-bound organelles (e.g. mitochondria); a human cell does.Another prokaryote/eukaryote difference.
  3. A virus cannot respire, grow or reproduce by itself.It lacks the machinery of a cell.
  4. It can only replicate inside a host cell, so it does not meet the criteria for life.Independent life processes are needed to be called living.

Bacteria lack a nucleus and membrane-bound organelles (unlike human cells); a virus is non-living because it cannot carry out life processes without hijacking a host cell.

05

How bacteria cause — and fight — disease

Some bacteria are pathogens: they invade the body, multiply rapidly and often release poisons (toxins) that damage tissues, causing diseases like cholera, tuberculosis and tetanus. The body defends itself with white blood cells, and doctors treat bacterial infection with antibiotics, which kill bacteria or stop them dividing. Overusing antibiotics, however, breeds resistant strains — so they must be used carefully. Antibiotics have no effect on viral diseases.

06

Bacteria that help us

Most bacteria are harmless or useful. As decomposers they recycle nutrients from dead matter; nitrogen-fixing bacteria in the soil and in root nodules turn nitrogen gas into compounds plants can use; and in industry bacteria make yoghurt and cheese, antibiotics, and — through genetic engineering — medicines such as insulin. Their fast growth and simple needs make them ideal microscopic factories.

Most microbes are friends

Only a minority of bacteria are pathogens. Far more are essential — recycling nutrients, fixing nitrogen for plants, and making our food and medicines.

Practice questions

4 questions · 16 marks · full working on every one

Try each one on paper first, then open the working. The marks are shown where they are actually awarded, because that is where they are actually lost.

Short questions

2 · 5 marks

Two marks each, in the style of the short-question section of the paper. Answer in two or three lines.

SQ1[3 marks]
State three features of a bacterial (prokaryotic) cell.
Model answer

Any three: no nucleus (DNA is a free circular loop); no membrane-bound organelles; a cell wall; sometimes plasmids or a flagellum; reproduces by binary fission.

Examiner tip. Focus on what makes it prokaryotic — no nucleus, no organelles.

SQ2[2 marks]
Explain why antibiotics can treat a bacterial infection but not a viral one.
Model answer

Antibiotics target structures and processes found in bacteria (such as the cell wall), killing them or stopping them dividing. Viruses have no such structures and replicate inside the body's own cells, so antibiotics cannot affect them.

Examiner tip. Antibiotics hit bacterial structures viruses lack.

Long questions

2 · 11 marks

Theory and numerical together, as they appear in the long-question section.

LQ1[6 marks]
Viruses and bacteria both cause disease but are very different.
  1. Describe the structure of a virus. [2]
  2. Explain why a virus is not considered a living organism. [2]
  3. Explain why antibiotics work on bacterial but not viral infections. [2]
Mark scheme
  1. A virus is genetic material (DNA or RNA)[1]
  2. surrounded by a protein coat[1]
  3. It cannot respire, grow or reproduce by itself[1]
  4. it only replicates inside a host cell[1]
  5. Antibiotics target bacterial structures/processes (e.g. cell walls)[1]
  6. viruses have no such structures and hide inside host cells, so antibiotics do not affect them[1]

A virus is nucleic acid in a protein coat; non-living because it needs a host to replicate; antibiotics hit bacterial structures viruses lack.

Examiner tip. Viruses lack the cellular machinery that antibiotics target.

LQ2[5 marks]
Bacteria have both harmful and beneficial roles.
  1. Describe how a pathogenic bacterium can make a person ill. [2]
  2. Describe two beneficial roles of bacteria. [3]
Mark scheme
  1. The bacterium invades and multiplies rapidly in the body[1]
  2. and releases toxins that damage tissues, causing symptoms[1]
  3. Decomposers break down dead matter, recycling nutrients[1]
  4. nitrogen-fixing bacteria convert nitrogen gas into compounds plants can use[1]
  5. and bacteria are used to make foods (yoghurt/cheese) or medicines (insulin/antibiotics)[1]

Pathogens multiply and release toxins that damage tissue; useful bacteria decompose, fix nitrogen and make food/medicine.

Examiner tip. Balance the one harmful role against two useful ones.